P. Aleksieva et S. Mutafov, CONTINUOUS-CULTURE OF HUMICOLA-LUTEA-120-5 FOR ACID PROTEINASE PRODUCTION, World journal of microbiology & biotechnology, 13(3), 1997, pp. 353-354
Acid proteinase production by the fungus Humicola lutea 120-5 in conti
nuous culture was studied. The maximum activity of the culture broth r
eached 2200 U/ml at a dilution rate (D) of 0.05/h. The continuous proc
ess was carried out for 1 month without any bacterial contamination, d
ue to low pH (3.0-3.5) during the cultivation.