Excitable media with twisted anisotropy have recently been attracting signi
ficant interest because of their applicability to wave propagation in heart
tissue. Here we consider the dynamics of an intramural scroll wave whose f
ilament lies initially within an arbitrary layer of mutually parallel cardi
ac fibers, and drifts parallel to itself from layer to layer. Earlier simul
ations have demonstrated that such a filament stabilizes in a layer whose f
iber direction is the same as its own. In the present paper we analytically
derive the trajectory of the filament, and obtain good agreement with earl
ier numerical data. For sufficiently sparse scrolls, our analysis predicts
an equilibrium alignment perpendicular rather than parallel to the fibers.