The behaviour of some estrogens in the nitration process. II. A comparative study of 18-crown-6-ether effect on estrone nitration with NO2, NO2+, HNO2 and NO2- species

Authors
Luca, C Nourescu, D Caproiu, MT Pencu, GI Constantinescu, T
Citation
C. Luca et al., The behaviour of some estrogens in the nitration process. II. A comparative study of 18-crown-6-ether effect on estrone nitration with NO2, NO2+, HNO2 and NO2- species, REV RO CHIM, 44(2), 1999, pp. 147-153
Citations number
17
Categorie Soggetti
Chemistry
Journal title
REVUE ROUMAINE DE CHIMIE
ISSN journal
00353930 → ACNP
Volume
44
Issue
2
Year of publication
1999
Pages
147 - 153
Database
ISI
SICI code
0035-3930(199902)44:2<147:TBOSEI>2.0.ZU;2-7
Abstract
The estrone 1 conversion by nitration and the percentage of nitroderivative s obtained, i.e. 2-nitroestrbone 2, 4-nitroestrone 3 and 2,4-dinitroestrone 4, depend on the nitration procedure used (through NO2+, HNO2, NO2 gas or NO2- anion in the presence of crown ether 18C6, respectively). The dinitrod erivative 4 was obtained Only iu the nitration process by means of NO2 gas. Estrone 1 was also nitrated with NO2- anion in the presence of valinomycin antibiotic macrocyclic ionophore; the procedure was identical to that adop ted for 18C6.