An efficient "one pot" synthesis of isoflavones

Citation
S. Balasubramanian et Mg. Nair, An efficient "one pot" synthesis of isoflavones, SYN COMMUN, 30(3), 2000, pp. 469-484
Citations number
37
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
3
Year of publication
2000
Pages
469 - 484
Database
ISI
SICI code
0039-7911(2000)30:3<469:AE"PSO>2.0.ZU;2-P
Abstract
Initial formation of deoxybenzoin 3 from phenyl acetic acid 1 and phenol 2 in the presence of BF3.Et2O followed by its treatment at room temperature w ith N, N'-dimethyl (chloromethylene) ammonium chloride, generated by reacti ng PCI, with DMF provides a mild and efficient route for a "one pot" synthe sis of Isoflavones in high yields.