Synthesis of 4-(p-methoxyphenyl)-beta-carboline, a new inhibitor of cellular calcium influx

Authors
Busacca, CA Dong, Y
Citation
Ca. Busacca et Y. Dong, Synthesis of 4-(p-methoxyphenyl)-beta-carboline, a new inhibitor of cellular calcium influx, SYN COMMUN, 30(3), 2000, pp. 501-509
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
3
Year of publication
2000
Pages
501 - 509
Database
ISI
SICI code
0039-7911(2000)30:3<501:SO4ANI>2.0.ZU;2-T
Abstract
4-(p-methoxyphenyl)-beta-carboline was prepared in four steps from indole. The key step involved palladium-catalyzed dehydrogenation of a dihydro-beta -carboline dichlorophosphinic acid salt. The success of the dehydrogenation was found to depend on the catalyst support.