The importance of the adipozyte hormone for the regulation of food intake,metabolism and reproduction

Citation
E. Kolb et al., The importance of the adipozyte hormone for the regulation of food intake,metabolism and reproduction, TIER UMSCH, 55(2), 2000, pp. 79-84
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
TIERARZTLICHE UMSCHAU
ISSN journal
00493864 → ACNP
Volume
55
Issue
2
Year of publication
2000
Pages
79 - 84
Database
ISI
SICI code
0049-3864(20000201)55:2<79:TIOTAH>2.0.ZU;2-A
Abstract
Leptin, a hormone of adipocytes, is a low molecular protein comprising 146 amino acids. After binding to receptors is elicits an activation of protein kinases and of transcription. Receptors exist in most tissues. An increase in the proportion of adipose tissue in the body and in the content of Lept in in the plasma inhibit food intake by influencing the synthesis of neurop eptides in the hypothalamus and therefore of neuropeptide Y. Leptin increas es the secretion of various hormones and the oxidation of glucose and fatty acids and results in reducing the secretion and lipogenetic activity of in sulin. It stimulates the secretion of LH releasing hormone, FSH and LH, and the maturation and function of the reproductive organs.