Regulation of endocytic traffic by Rho family GTPases

Endocytosis is a complicated yet highly efficient process that involves the uptake and processing of cargoes, ranging from small molecules, to activat ed signalling receptors, to whole microorganisms. Regulation of endocytic p athways is poorly understood. Recent evidence suggests that the Rho GTPase family of signalling protein is intimately involved in endocytic traffic, p roviding novel insights into the control mechanisms that govern this proces s.