Use of Tc-99m-mercaptoacetyltriglycine to evaluate renal function in horses

Authors
Woods, PR Drost, WT Clarke, CR Rodebush, CJ
Citation
Pr. Woods et al., Use of Tc-99m-mercaptoacetyltriglycine to evaluate renal function in horses, VET RAD ULT, 41(1), 2000, pp. 85-88
Citations number
16
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
VETERINARY RADIOLOGY & ULTRASOUND
ISSN journal
10588183 → ACNP
Volume
41
Issue
1
Year of publication
2000
Pages
85 - 88
Database
ISI
SICI code
1058-8183(200001/02)41:1<85:UOTTER>2.0.ZU;2-U
Abstract
Ten healthy horses were injected intravenously with Tc-99m-MAG(3) and the d isappearance of radioactivity from the blood was measured, The total body c learance (Cl-B) and elimination half-life (t(1/2(beta))) were 7.9 +/- 1.5 m l/kg/minute and 32.8 +/- 4.1 minutes, respectively. The disappearance of Tc -99m-MAG(3) from the blood of 2 horses with compromised renal function was also measured. The data suggest that Tc-99m-MAG(3) is a useful and clinical ly applicable radiopharmaceutical for measurement of effective renal blood flow in the horse.