Two new antifungal withanolides (1) and (2) have been isolated from the def
atted methanolic extract of Ajuga parviflora. Their structures were establi
shed as 3 beta,1 beta,20-trihydroxy-1-oxo -(20R, 22R)-witha-5,13,24-trienol
ide (1), 28-hydroxy-14,20-epoxy-1 -oxo-(22R)-witha-2,5,24-trienolide (2) on
the basis of spectroscopic data including two dimensional NMR techniques.
The pyrrolizidine alkaloids senecionine (3) and integerrimine (4) are also
reported for the first time from A. parviflora.