The acknowledged early adoption of placebo controls in drug trials by homeo
paths is currently thought to have been derived from prior external attempt
s to discredit the system. This claim is reexamined in the light of a compr
ehensive literature search for 29th-century homeopathic therapeutic trials
and provings using placebo. Single blind placebo controls, still used today
, are shown to have originated independently, within homeopathy's own disci
plinary matrix before the first external evaluations. They are the most lik
ely source for later placebo-controlled crossover and parallel group experi
ments by homeopaths.