Electrospray ionization time-of-flight mass spectrometric detection for fast liquid phase separations

Authors
Lazar, IM Lee, ED Sin, JCH Rockwood, AL Onuska, KD Lee, ML
Citation
Im. Lazar et al., Electrospray ionization time-of-flight mass spectrometric detection for fast liquid phase separations, AM LABORAT, 32(3), 2000, pp. 110
Citations number
34
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
AMERICAN LABORATORY
ISSN journal
00447749 → ACNP
Volume
32
Issue
3
Year of publication
2000
Database
ISI
SICI code
0044-7749(200002)32:3<110:EITMSD>2.0.ZU;2-3
Abstract
For the chromatogrpaher, TOF mass spectrometry has added new dimensions to MS detection. In addition to providing unequivocal qualitative analysis, TO F adds sensitivity and speed. Complete mass spectra can be generated with a frequency of 5-10 kHz. This now provides the capability of signal averagin g, single ion monitoring, and the ability to monitor fast separations with very narrow peaks.