D. Subrahmanyam et al., Novel C-ring analogues of 20(S)-camptothecin. Part 3: Synthesis and their in vitro cytotoxicity of A-, B- and C-ring analogues, BIOORG MED, 10(4), 2000, pp. 369-371
Several 5-substituted alkoxy 20(S)-camptothecin analogues having A- and B-r
ing substituents were prepared via semisynthesis. Most of these compounds w
ere found to exhibit potent anti-cancer activity based on their in vitro cy
totoxicity data obtained against human tumor cell lines. (C) 2000 Elsevier
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