Carbamazepine-induced systemic lupus erythematosus presenting as cardiac tamponade

Here we report the case of a patient who presented with acute cardiac tampo nade due to drug-induced systemic lupus erythematosus (SLE). The patient ha d been treated for a seizure disorder with carbamazepine, a chug that has p reviously been demonstrated to cause SLE-like syndromes, Further serologic anal, sis demonstrated the likelihood of drug-induced SLE in this patient, with the rare presentation of cardiac tamponade.