The genetic control of organ growth: insights from Drosophila

Authors
Weinkove, D Leevers, SJ
Citation
D. Weinkove et Sj. Leevers, The genetic control of organ growth: insights from Drosophila, CUR OP GEN, 10(1), 2000, pp. 75-80
Citations number
52
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959437X → ACNP
Volume
10
Issue
1
Year of publication
2000
Pages
75 - 80
Database
ISI
SICI code
0959-437X(200002)10:1<75:TGCOOG>2.0.ZU;2-A
Abstract
The genetic control of growth ensures that animals grow to reproducible siz es and that tumourous growth is rare. This year, the regulation of organ gr owth has been studied extensively in Drosophila imaginal discs, and a signa lling pathway that regulates organ growth and size has been identified. Fur thermore, the role of Drosophila homologues to human tumour suppressor gene s and oncogenes in imaginal disc growth has been investigated.