Reductive biotransformation of diethyl beta-, gamma- and delta-oxoalkylphosphonates by cells of baker's yeast

Authors
Zymanczyk-Duda, E Kafarski, P Lejczak, B
Citation
E. Zymanczyk-duda et al., Reductive biotransformation of diethyl beta-, gamma- and delta-oxoalkylphosphonates by cells of baker's yeast, ENZYME MICR, 26(2-4), 2000, pp. 265-270
Citations number
29
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
ENZYME AND MICROBIAL TECHNOLOGY
ISSN journal
01410229 → ACNP
Volume
26
Issue
2-4
Year of publication
2000
Pages
265 - 270
Database
ISI
SICI code
0141-0229(200002)26:2-4<265:RBODBG>2.0.ZU;2-U
Abstract
Enantiomerically pure hydroxyalkylphosphonates (over 95% of enantiomeric ex cess) were obtained by asymmetric reductive biotransformation of a variety of oxoalkylphosphonates catalyzed by baker's yeast. In the most cases the b iotransformations were carried out in water under aerobic conditions using whole cell system. In the case of compounds unreactive under these conditio ns the anaerobic reduction was applied. (C) 2000 Elsevier Science Inc. All rights reserved.