The expression of DAZL1 in the ovary of the human female fetus

Authors
Tsai, MY Chang, SY Lo, HY Chen, IH Huang, FJ Kung, FT Lu, YJ
Citation
My. Tsai et al., The expression of DAZL1 in the ovary of the human female fetus, FERT STERIL, 73(3), 2000, pp. 627-630
Citations number
20
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
FERTILITY AND STERILITY
ISSN journal
00150282 → ACNP
Volume
73
Issue
3
Year of publication
2000
Pages
627 - 630
Database
ISI
SICI code
0015-0282(200003)73:3<627:TEODIT>2.0.ZU;2-L
Abstract
Objective: To determine whether DAZL1 is expressed in human fetal ovarian t issue. Design: The presence of DAZL1 expression was determined by reverse transcri ptase polymerase chain reaction (RT-PCR). Setting: Academic tertiary care medical center and research unit of univers ity. Patient(s): Five female abortuses between the 19th and 22nd week of gestati onal age. Intervention(s): Fetal ovarian tissues were collected immediately after the cessation of the heart beat. Main Outcome Measure(s): The product of RT-PCR. Result(s): DAZL1 expression was detected in all five samples. Conclusion(s): DAZL1 is not only expressed in human testes but also in ovar ies. It may play a role in germ cell survival and gonad development in both sexes. American Society for Reproductive Medicine.