Thirty-nine patients with factor XI deficiency were diagnosed in our genera
l hospital, which serves all the French Basque Country (about 290 000 inhab
itants), between 1985 and 1995. Biological and clinical data of these cases
are reported herein. Factor XI deficiency seems significantly more frequen
t in Basques than in the other non-Ashkenazi populations. Molecular studies
should be performed for typing these cases in the view of population genet
ics.