G. Zadeii et Jw. Lohr, RENAL PAPILLARY NECROSIS IN A PATIENT WITH SICKLE-CELL TRAIT, Journal of the American Society of Nephrology, 8(6), 1997, pp. 1034-1039
A patient with sickle cell trait who presented with gross hematuria an
d was subsequently found to have renal papillary necrosis is presented
. The hematuria resolved with conservative therapy consisting of bed r
est and hydration with hypotonic intravenous fluids. The pathophysiolo
gy of renal abnormalities associated with sickle cell trait is describ
ed. The management of the primary clinical manifestations of this diso
rder, hematuria and papillary necrosis, are discussed.