Reversed-phase liquid chromatographic column switching for the determination of N-methylcarbamates and some of their main metabolites in urine

Citation
Pp. Vazquez et al., Reversed-phase liquid chromatographic column switching for the determination of N-methylcarbamates and some of their main metabolites in urine, J CHROMAT B, 738(2), 2000, pp. 387-394
Citations number
22
Categorie Soggetti
Chemistry & Analysis
Journal title
JOURNAL OF CHROMATOGRAPHY B
ISSN journal
13872273 → ACNP
Volume
738
Issue
2
Year of publication
2000
Pages
387 - 394
Database
ISI
SICI code
1387-2273(20000211)738:2<387:RLCCSF>2.0.ZU;2-A
Abstract
A column switching system for the determination of some polar pesticides an d their main metabolites, such as aldicarb, aldicarb sulphoxide, aldicarb s ulphone, carbofuran and 3-hydroxicarbofuran, in human urine has been develo ped, The limits of detection were between 0.3 and 1 mu g/l. We used a simpl e solid-phase extraction with graphite carbon and a RPLC-LC analysis with U V detection yielding average recoveries between 84 and 110% (N=5) with RSD between 4 and 8%. (C) 2000 Elsevier Science B.V. All rights reserved.