On the occasion of a case of dermatofibroma with histological lichenoid fea
tures, we reviewed from our files all the cases in which the epidermis, usu
ally hyperplastic in dermatofibroma, was, in some was, partially or complet
ely destroyed. Among a total of 484 dermatofibromas, we found three licheno
id, six erosive and two ulcerated cases. In the three lichenoid cases, the
columnar epidermal basal cells were lacking (squamotization of the basal la
yer) and in two of them there was a cleft between the epidermis and the der
matofibroma. Three of the six eroded cases were large pedunculated dermatof
ibromas with inflammatory phenomena of variable intensity. One case was in
the center of a plaque of lichen simplex chronicus with some eroded area. I
n the other two cases, as well as in the two ulcerated lesions, neither inf
lammation nor epidermal changes usually attributed to rubbing or scratching
were seen. Only in three of the eleven cases dermatofibroma was proposed (
with question mark) as a clinical diagnosis. Both followup and histopatholo
gy supported the benign nature of these cases. We may conclude that: i) Lic
henoid, erosive and ulcerated changes in dermato fibroma are infrequent phe
nomena which may make a clinical diagnosis difficult; and ii) in the presen
ce of an otherwise histopathologically typical dermatofibroma, erosion and
ulceration should not be considered as suspicious of malignancy.