Z. Holub et L. Kliment, The effectiveness of collagen fleece combined with a fibrin glue in hemostasis during laparoscopic surgery, J GYNECOL S, 15(4), 1999, pp. 185-191
The object of this study was to evaluate the usefulness of TachoComb (TC),
a new hemostyptic agent that combines the advantages of two reliable hemost
yptic products, collagen fleece and fibrin glue, in local hemostasis during
laparoscopy. A total of 16 patients underwent local hemostatic treatment d
uring laparoscopic surgery. Ten patients were selected as an control group.
Patients were assessed in the,areas of efficacy, safety, utility, and appl
icability of TC after primary hemostatic treatment by electrosurgery and cl
ip techniques. Clinical data and the degree of hemostatic effect of the ass
essed drug were measured. All procedures were successfully completed. There
was no incidence of complications. The drug proved to be effective and use
ful in 100% of cases. No case was observed in which safety was problematic.
There were only two cases in which-application was problematic. Complete h
emostasis in the control group was obtained in only 80% of cases. The avera
ge hospital stay was 3.1 days (range 2-5). Clinical studies demonstrated th
at hemorrhage from damaged tissue near important pelvic structures can be s
uccessfully arrested and controlled using the laparoscope to apply TachoCom
b. At present, 16 patients have been effectively treated with collagen-fibr
in agent during laparoscopic surgery. The elimination of hemorrhage after p
rimary laparoscopic electrosurgery and the effectiveness of this drug were
tested. The results show that the efficacy of TC in local hemostasis is exc
ellent.