Hydrates of thiothixene center dot 2HCl: Kinetics of dehydration and crystal structure of the methanol solvate

Authors
Bourne, SA Coetzee, A Jacobs, A
Citation
Sa. Bourne et al., Hydrates of thiothixene center dot 2HCl: Kinetics of dehydration and crystal structure of the methanol solvate, J INCL P MA, 36(2), 2000, pp. 217-228
Citations number
10
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY
ISSN journal
13883127 → ACNP
Volume
36
Issue
2
Year of publication
2000
Pages
217 - 228
Database
ISI
SICI code
1388-3127(200002)36:2<217:HOTCD2>2.0.ZU;2-H
Abstract
Thiothixene . 2HCl forms three different hydrates on exposure to water vapo ur. These have been characterised by X-ray powder diffraction. The dehydrat ion reaction of the monohydrate follows the first-order rate law with E-a = 125(22) kJ mol(-1). The dehydration of the tetrahydrate follows a complex mechanism. The crystal structure of the methanol solvate of thiothixene . 2 HCl has been elucidated. It is monoclinic, P2(1)/c, a = 18.870, b = 7.018, c = 21.913 Angstrom, beta = 105.622 degrees.