Primary Sjogren's syndrome manifested as multiple sclerosis and cutaneous erythematous lesions: A case report

Sjogren's syndrome is a chronic autoimmune disorder characterized by lympho cytic infiltration of the lacrimal and salivary glands, leading to dryness of eyes (kerato-conjunctivitis sicca) and mouth (xerostomia). The skin lesi ons in Sjogren's syndrome are usually manifested as xeroderma, but sometime s appear as annular erythema or vasculitis. Central nervous system symptoms may be presented as one of extraglandular manifestations, though rare in i ncidence, and need differential diagnosis from multiple sclerosis. We repor t a case of a 45-year-old woman diagnosed as multiple sclerosis at first bu t later as neurologic manifestation of primary Sjogren's syndrome, showing signs of multiple sclerosis and cutaneous erythematous lesions.