Novel polycyclic guanidine alkaloids from two marine sponges of the genus Monanchora

Authors
Braekman, JC Daloze, D Tavares, R Hajdu, E Van Soest, RWM
Citation
Jc. Braekman et al., Novel polycyclic guanidine alkaloids from two marine sponges of the genus Monanchora, J NAT PROD, 63(2), 2000, pp. 193-196
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
2
Year of publication
2000
Pages
193 - 196
Database
ISI
SICI code
0163-3864(200002)63:2<193:NPGAFT>2.0.ZU;2-X
Abstract
Two marine sponges of the genus Monanchora (Poecilosclerida, Crambeidae) ha ve been found to contain new polycyclic guanidine alkaloids bearing the (5, 6,8b)-triazaperhydroacenaphthylene skeleton. Their structures have been det ermined by detailed spectroscopic analysis. Dehydrobatzelladine C (1) has b een isolated from M. arbuscula and crambescidins 359 (2) and 431 (3) from M . unguiculata. The chemotaxonomic implications of these findings are discus sed.