Dolastatin 3 and two novel cyclic peptides from a Palauan collection of Lyngbya majuscula

Authors
Mitchell, SS Faulkner, DJ Rubins, K Bushman, FD
Citation
Ss. Mitchell et al., Dolastatin 3 and two novel cyclic peptides from a Palauan collection of Lyngbya majuscula, J NAT PROD, 63(2), 2000, pp. 279-282
Citations number
13
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
63
Issue
2
Year of publication
2000
Pages
279 - 282
Database
ISI
SICI code
0163-3864(200002)63:2<279:D3ATNC>2.0.ZU;2-Q
Abstract
A collection of Lyngbya majuscula from Palau contained the peptides dolasta tin 3 (1), homodolastatin 3 (2), and kororamide (3), together with aplysiat oxin (4), debromoaplysiatoxin (5), and oscillatoxin A (6). The structures o f the new peptides homodolastatin 3 (2) and kororamide (3) were determined by interpretation of spectroscopic data and chemical degradation.