Several structural analogues of the biocompatible diacyl glycerol phosphati
dylcholine family have been prepared. Considerable variation in structure i
s allowed without impairing the desirable biocompatible properties. In part
icular, derivatives in which the fatty ester link is replaced by ether link
s and in which the central glycerol group is replaced by simple variants su
ch as the symmetrical tris(hydroxymethyl)ethane group retain biocompatible
properties.