On the preparation of some phospholipid analogues

Citation
Je. Browne et al., On the preparation of some phospholipid analogues, J CHEM S P1, (5), 2000, pp. 645-652
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Issue
5
Year of publication
2000
Pages
645 - 652
Database
ISI
SICI code
0300-922X(2000):5<645:OTPOSP>2.0.ZU;2-H
Abstract
Several structural analogues of the biocompatible diacyl glycerol phosphati dylcholine family have been prepared. Considerable variation in structure i s allowed without impairing the desirable biocompatible properties. In part icular, derivatives in which the fatty ester link is replaced by ether link s and in which the central glycerol group is replaced by simple variants su ch as the symmetrical tris(hydroxymethyl)ethane group retain biocompatible properties.