Providing biocatalysts through customizing lipases by different processes

The author is recalling first mechanisms of lipase catalyzed reactions. Hyd rolyses and syntheses of triglycerides and esters, interesterification : ge nerally these types of reactions are designed under the generic designation of acyl transfers. Enzymatic reactions are equilibrated and then the displ acement of the reaction in one or the other direction is highly depending o n the thermodynamic activity of water (a(w)). This notion is discussed in d epth. It is also emphasized on the quantity and quality of interface and al so on the concept of pH memory or ionic force memory of the aqueous phase e ven whether this last is confined or invisible. Lipases selectivity is espe cially developed and the author emphasizes on the possibility of changing s electivities through different perturbations. Physical and chemical modific ations of lipases are then described throught the more pedagogic and specta cular examples. The author is also stressing on the mastership of reactions and processes imposing a task to lipases. He is finally concluding that in the space of fifty years, one ascertains a colossal work has been accompli shed and that henceforward very current reactions for commodity products or e available as certain companies are already doing. He is pointing out plant lipases are on the verge to meet deep and unexpect ed developments in a very near future since their production through agricu lture is probably the lower cast mean ai production.