Synthesis of multiply substituted, ion channel forming octi(p-phenylene)s:Theme and variations

Authors
Robert, F Winum, JY Sakai, N Gerard, D Matile, S
Citation
F. Robert et al., Synthesis of multiply substituted, ion channel forming octi(p-phenylene)s:Theme and variations, ORG LETT, 2(1), 2000, pp. 37-39
Citations number
37
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
1
Year of publication
2000
Pages
37 - 39
Database
ISI
SICI code
1523-7060(200001)2:1<37:SOMSIC>2.0.ZU;2-1
Abstract
[GRAPHICS] To facilitate the access to unique models for biological processes, we exam ined six different synthetic routes to octi(p-phenylene) rods with lateral and terminal substitutents R-L and R-T. This systematic study allowed us to increase to overall yield for the synthesis of a new class of oligo(p-phen ylene) ionophores about 20 times and to provide general insights into the p racticability of synthetic routes to multiply substituted molecular rods.