Palladium-catalyzed arylation of alpha-methylene-gamma-butyrolactone: 3-benzylfuran-2(5H)-ones vs (Z)-benzylidene-gamma-butyrolactones and their reduction to 3-benzyl-gamma butyrolactones

Authors
Arcadi, A Chiarini, M Marinelli, F Berente, Z Kollar, L
Citation
A. Arcadi et al., Palladium-catalyzed arylation of alpha-methylene-gamma-butyrolactone: 3-benzylfuran-2(5H)-ones vs (Z)-benzylidene-gamma-butyrolactones and their reduction to 3-benzyl-gamma butyrolactones, ORG LETT, 2(1), 2000, pp. 69-72
Citations number
37
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
1
Year of publication
2000
Pages
69 - 72
Database
ISI
SICI code
1523-7060(200001)2:1<69:PAOA3>2.0.ZU;2-1
Abstract
[GRAPHICS] The palladium-catalyzed arylation of the alpha-methylene-gamma-butyrolacton e proceeds in good yields and may be directed toward the synthesis of 3-ben zylfuran-2(5H)-ones when the starting aryl iodides contain strongly electro n withdrawing groups. The combined palladium-catalyzed arylation/hydrogenat ion of the alpha-methylene-gamma-butyrolactone represents a new simple entr y into functionalized alpha-benzyl-gamma-butyrolactones.