Let F : M3 --> R-5 be an embedding of an (oriented) Z(2)-homology 3-sphere
M-3 in R-5. Then F bounds an embedding of an oriented manifold W-4 in R-5.
It is well known that the signature sigma(W-4) of W-4 is equal to the mu-in
variant of M-3 modulo 16. In this paper we prove that sigma(W-4) itself com
pletely determines the regular homotopy class of F.