ANTIFUNGAL ACTIVITY OF ORGANIC AND ORGANOMETALLIC DERIVATIVES OF BENZIMIDAZOLE AND BENZOTHIAZOLE

Authors
KUCUKBAY H DURMAZ B
Citation
H. Kucukbay et B. Durmaz, ANTIFUNGAL ACTIVITY OF ORGANIC AND ORGANOMETALLIC DERIVATIVES OF BENZIMIDAZOLE AND BENZOTHIAZOLE, Arzneimittel-Forschung, 47(5), 1997, pp. 667-670
Citations number
29
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Arzneimittel-Forschung → ACNP
ISSN journal
00044172
Volume
47
Issue
5
Year of publication
1997
Pages
667 - 670
Database
ISI
SICI code
0004-4172(1997)47:5<667:AAOOAO>2.0.ZU;2-J
Abstract
Forty organic or organometallic derivatives of benzimidazole and benzo thiazole and five rhodium(I) and ruthenium(Ir) complexes were evaluate d for their in vitro antifungal activity against Candida albicans. Fou r of the tested compounds, the rhodium containing compounds 30, 31, 32 and 33, were found effective at the minimum inhibitory concentrations (MICs) between 400-600 mu g/ml.