Formaldehyde (GAS RN 50-00-0) is a simple, commonly occurring chemical
and a frequent contact allergen. Studies on exposure to formaldehyde
in patients with contact dermatitis and sensitivity to formaldehyde sh
owed that both products containing formaldehyde and formaldehyde relea
sing preservatives were frequent sources of formaldehyde exposure. In
a survey on hazardous chemicals in Danish industry formaldehyde was mo
stly consumed in the industry group ''manufacture of non-metallic mine
ral products'' followed by ''manufacture of fabricated metal products'
'. The industry groups with the highest estimated numbers of exposure
events causing contact with formaldehyde were ''personal services, cle
aning, and hair dressing'', ''manufacture of fabricated metal products
'', ''painters and carpenters''. In studies on contact allergens in ch
emical products using the Danish Product Register Database (PROBAS) fo
rmal dehyde was most frequently registered in paints/lacquers followed
by binders (polymers) and cleaning agents. The most frequent product
categories registered with formaldehyde-releasers were cleaning agents
, soap, shampoo, paints/lacquers and metal working fluids. In a study
on cleaning agents for industrial and household purpose isothiazolinon
es and formaldehyde-releasers were the most commonly registered preser
vatives. The value and use of the different sources of information on
formaldehyde exposure depend on the source of formaldehyde in the prod
uct and the connection in which the information is needed, e.g. clinic
al treatment of patients, risk assessment for the whole population or
legislation on restriction of allergen exposure. This paper focuses on
sources of formaldehyde exposure relevant to skin exposure and contac
t allergy to formaldehyde, primarily chemical products with relatively
low formaldehyde concentration. The paper presents information on sou
rces of formaldehyde exposure based on: different exposure situations,
which substances to look for, sources of formaldehyde besides compone
nts, industry groups and product categories. This information may help
to elucidate the exposure in cases of allergy to formaldehyde and in
the process of eliminating or reducing further exposure.