Study Design. Multicenter, prospective, observational study.
Objectives, To document the incidence of and factors associated with intrav
ascular uptake during lumbar spinal injection procedures.
Summary of Background Data. In prior reports, the incidence of inadvertent
intravascular needle placement during contrast-enhanced, fluoroscopically g
uided lumbar spinal injection procedures has been incidentally noted to ran
ge from 6.4% to 9.2%. We present the first systematic prospective documenta
tion of intravascular uptake of contrast dye during different types of lumb
ar injection procedures.
Methods. Fifteen interventional spine physicians in seven centers recorded
data regarding intravascular uptake:during 1219 contrast-enhanced, fluorosc
opically guided lumbar spinal injection procedures.
Results. The overall incidence of intravascular uptake during lumbar spinal
injection procedures as determined by contrast enhanced fluoroscopic obser
vation is 8.5%, Caudal and transforaminal routes have the highest rates at
10.9% and 10.8%, respectively, followed by zygapophyseal joint (6.1%), sacr
oiliac joint (5.3%), and translaminar (1.9%) injections. Intravascular upta
ke is twice as likely to occur in those patients over rather than under 50
years of age, Preinjection aspiration failed to produce a flashback of bloo
d in 74% of cases that proved to be intravascular upon injection of contras
t dye.
Conclusion. The incidence of intravascular uptake during lumbar spinal inje
ction procedures is approximately 8.5%. The route of injection and the age
of the patient greatly affect this rate. Absence of flashback of blood upon
preinjection aspiration does not predict extravascular needle placement. C
ontrast-enhanced, fluoroscopic guidance is recommended when doing lumbar sp
inal injection procedures to prevent inadvertent intravascular uptake of in
jectate.