It has been widely noted that vitamin E shows numerous beneficial effects t
hrough and beyond its antioxidative properties, consequently, vitamin E is
expected to prevent degenerative diseases. In the field of sports medicine,
many studies dealing with vitamin E have been conducted originally from th
e point of view of its effects on physical performance. Although some earli
er studies indicated that vitamin E supplementation could improve physical
performance, defects in the study design or statistical analysis were point
ed out at a later time. The majority of subsequent well controlled studies
have reported no significant effect on physical performance from vitamin E
supplementation. Recent studies suggest that endurance exercise may promote
free radical generation in the body, and vitamin E may play an important r
ole in preventing the free radical damage associated with endurance exercis
e. Although there is evidence of free radical involvement in exercise-induc
ed muscle injury, vitamin E supplementation might not be expected to preven
t muscle damage caused by exercise in humans without a vitamin E deficiency
. Since it is;Still unclear whether exercise induces lipid peroxidation in
the human body, the beneficial effect of vitamin E supplementation on exerc
ise-induced lipid peroxidation has not yet been established. However, it is
proposed that as a result of exercise vitamin E may be mobilised from stor
e tissues and redistributed in the body to prevent oxidative damage. Theref
ore, we are convinced that vitamin E contributes to preventing exercise-ind
uced lipid peroxidation. It has also been indicated that strenuous enduranc
e exercise may enhance the production of oxidised low density lipoprotein (
LDL), which plays a key role in the initiation and progression of atheroscl
erosis. It is also suggested that this enhanced production of oxidised LDL
could be reduced if a higher vitamin E status is maintained. Supplementatio
n with 100 to 200mg of vitamin E daily can be recommended for all endurance
athletes to prevent exercise-induced oxidative damage and to reap the full
health benefits of exercise.