A practical and efficient intramolecular Michael addition of ureas to alpha,beta-unsaturated esters

Authors
Xin, ZL Pei, ZH von Geldem, T Jirousek, M
Citation
Zl. Xin et al., A practical and efficient intramolecular Michael addition of ureas to alpha,beta-unsaturated esters, TETRAHEDR L, 41(8), 2000, pp. 1147-1150
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
8
Year of publication
2000
Pages
1147 - 1150
Database
ISI
SICI code
0040-4039(20000219)41:8<1147:APAEIM>2.0.ZU;2-I
Abstract
A mild and efficient method is described for the synthesis of dihydroquinaz oline derivatives via intramolecular hetero-Michael addition of ureas to or tho-substituted alpha,beta-unsaturated esters in the presence of NaOH in TH F with high chemical yield. (C) 2000 Elsevier Science Ltd. All rights reser ved.