Enantiopure aminoiodohydrins obtained from a-aminoaldehydes and Sm/CH2I2 ha
ve been transformed into regioisomeric aminoiodohydrins, aminoepoxides, aze
tidines or 1,3-oxazolidines. The key step in these transformations is a nuc
leophilic opening-closing process. (C) 2000 Elsevier Science Ltd. All right
s reserved.