Nucleophilic reactivity of perhydro-3,6,9,12-tetraazacyclopenteno[1,3-f,g]acenaphthylene. A unified approach to N-monosubstituted and N,N ''-disubstituted cyclene derivatives

Authors
Rohovec, J Gyepes, R Cisarova, I Rudovsky, J Lukes, I
Citation
J. Rohovec et al., Nucleophilic reactivity of perhydro-3,6,9,12-tetraazacyclopenteno[1,3-f,g]acenaphthylene. A unified approach to N-monosubstituted and N,N ''-disubstituted cyclene derivatives, TETRAHEDR L, 41(8), 2000, pp. 1249-1253
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
8
Year of publication
2000
Pages
1249 - 1253
Database
ISI
SICI code
0040-4039(20000219)41:8<1249:NROP>2.0.ZU;2-X
Abstract
Perhydro-3,6,9,12-tetraazacyclopenteno[1,3-f,g] is readily mono- and dialky lated on nitrogen with alkyl bromides and iodides giving mono- and bis-quar ternary ammonium salts. The title compound is a unified starting material f or the preparation of cyclene based chelators. (C) 2000 Elsevier Science Lt d. All rights reserved.