Homologation of allylic alcohols. An approach to cyclic and acyclic polyoxygenated compounds

Authors
Davoille, RJ Rutherford, DT Christie, SDR
Citation
Rj. Davoille et al., Homologation of allylic alcohols. An approach to cyclic and acyclic polyoxygenated compounds, TETRAHEDR L, 41(8), 2000, pp. 1255-1259
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
8
Year of publication
2000
Pages
1255 - 1259
Database
ISI
SICI code
0040-4039(20000219)41:8<1255:HOAAAA>2.0.ZU;2-V
Abstract
The combination of the Sharpless asymmetric epoxidation reaction with a sul fur ylide mediated synthesis of allylic alcohols from epoxides provides a p owerful iterative process for the production of polyoxygenated compounds. T he alkene installed in the sulfur ylide reaction has also been used in a nu mber of ring closing metathesis reactions to produce highly oxygenated cycl ic compounds. (C) 2000 Elsevier Science Ltd. All rights reserved.