POSTOPERATIVE GNRH ANALOG TREATMENT FOR THE PREVENTION OF RECURRENCESOF UTERINE MYOMAS AFTER MYOMECTOMY - A PILOT-STUDY

Authors
VAVALA V LANZONE A MONACO A SCRIBANTI A GUIDA C MANCUSO S
Citation
V. Vavala et al., POSTOPERATIVE GNRH ANALOG TREATMENT FOR THE PREVENTION OF RECURRENCESOF UTERINE MYOMAS AFTER MYOMECTOMY - A PILOT-STUDY, Gynecologic and obstetric investigation, 43(4), 1997, pp. 251-254
Citations number
27
Categorie Soggetti
Obsetric & Gynecology
Journal title
Gynecologic and obstetric investigation → ACNP
ISSN journal
03787346
Volume
43
Issue
4
Year of publication
1997
Pages
251 - 254
Database
ISI
SICI code
0378-7346(1997)43:4<251:PGATFT>2.0.ZU;2-N
Abstract
Sixty-five patients with uterine myomas were studied after surgery to investigate the effect of periodic GnRH analog treatment on the preven tion of recurrences. A group of patients was treated by leuprolide ace tate depot 3 months a year for 3 years. At the end of treatment, these patients showed a significantly reduced uterine volume and myoma recu rrence rate as compared to untreated patients, A role of GnRH analogs in the clinical prevention of myoma recurrence could be suggested.