Isolated sphenoid sinus lesions

Pathologic conditions involving the sphenoid sinus alone are rare. A retros pective chart review was performed of 182 cases of isolated sphenoid sinus lesions seen at the Mayo Clinic between 1935 and 1998. There were 53 cases of sinusitis, 44 mucoceles, and 15 fungus-related cases (61.5%), and the we st of the cases were divided among numerous other pathologic entities. Symp toms, differential diagnosis, and various therapeutic modalities ai-e discu ssed We believe that these data will be useful to clinicians considering mu ltiple pathologic possibilities when faced with a lesion involving the sphe noid sinus alone.