Does the UICC classification of 1997 show a better prognostic value for ductal adenocarcinoma of the pancreas than the old classification?

Introduction: To compare treatment results an international established cla ssification is necessary. In 1997 the TNM classification of 1992 was modifi ed. Methods: Between 1983 and 1997, 159 patients with a ductal carcinoma of the pancreas underwent resection. All data of the resected specimens were documented in standardized manner prospectively in a protocol that offered ready transfer of the collected data to a new classification. The TNM categ ories and stage groupings were transferred to the new UICC classification o f 1997 and analyzed in comparison to the classification of 1992. Results: T he inclusion of a pT4 category equivalent to the other GI tumors made a new stage grouping necessary. Also division into pN1a and pN1b was established . According to the clinical experience only few tumors in early stages (pT1 /2 and stage I) were observed in the new classification. There was a signif icant improval in the patient's distribution to the new stage grouping beca use of the homogeneous groups. In comparison to the 1992 classification the new stage II shows a relevant prognostic value and a significant differenc e to stage III. Conclusion: We conclude that the new UICC classification re lates to prognosis better than the old classification.