With the advent of early weaning, gastrointestinal diseases of pigs have in
creased in significance and severity because of the need for land lack of)
excellent management, a proper living environment, and correctly formulated
diets. All of these factors are particularly important as passive immunity
to a number of gastrointestinal microorganisms expires during the nursery
period. Colibacillosis continues to be the leading cause of diarrhea in ear
ly weaners, frequently in combination with such viral agents as transmissib
le gastroenteritis virus or rotavirus. Large production systems require mas
s medication using antibiotics and electrolytes frequently administered via
water.