Efficacy and tolerability of a topical erythromycin/tretinoin combination preparation in acne treatment: Post-marketing surveillance study involving over 6500 patients

The good efficacy and tolerability of an alcoholic erythromycin/tretinoin s olution was confirmed in a multicentre data investigation of over 6500 pati ents. The mean score for comedones declined clearly from 1.9 to 0.9 during treatment (average duration 70 days). The score for papules and pustules wa s reduced from 1.6 to 0.5. Overall medical assessment indicated 'very good' to 'good' efficacy in 86.1% of documented cases. Adverse drug reactions du ring treatment were mostly only very mild and were nearly always the known symptoms of redness, scaling, dryness and itching. Overall assessment of to lerability was 'very good' or 'good' in 88.1% of cases.