D. Hammel et al., A SURVEY OF MECHANICAL MYOCARDIAL SUPPORT DEVICES 1997 - FROM INTRAAORTIC BALLOON COUNTERPULSATION TO IMPLANTABLE LEFT-VENTRICULAR ASSIST DEVICES, Anasthesist, 46(5), 1997, pp. 408-418
The development of cardiopulmonary bypass (CPB) to support the systemi
c circulation during cardiac surgical procedures became a clinical rea
lity in 1953. Although the use of CPB for the treatment of post-infarc
tion cardiogenic shock met with little success, intra-aortic balloon c
ounterpulsation was used successfully in 1968 to reduce ischaemic inju
ry in a patient with cardiogenic shock. Today, a broad spectrum of cir
culatory assist devi ces for short- and long-term application is avail
able. Three major indication groups for the use of support devices are
established. In low-cardiac-output syndrome after cardiac surgical pr
ocedures,short-term devices are utilised to enable myocardial recovery
. In transplantation candidates suffering from drug-resistant pump fai
lure, the implantation of long-term devices as a bridge to heart trans
plantation is indicated, and in NYHA class IV patients with contraindi
cations to heart transplantation, the implantation of long-term device
s as an alternative to transplantation is under discussion. In the lit
erature, post-cardiotomy sup port survival is less than 30% on average
. About 70% of mechanically bridged patients have survived to undergo
heart transplantation and were transplanted with over 90% survival. Ma
jor problems during mechanical support are infection, bleeding, and th
rombembolism. In View of patients' natural course without support, the
se clinical results are favourable.