Two comparative studies of dosmalfate vs. misoprostol in the prevention ofNSAID-induced gastric ulcers in rheumatic patients

Authors
de Lara, AC Gompel, H Valiente, R
Citation
Ac. De Lara et al., Two comparative studies of dosmalfate vs. misoprostol in the prevention ofNSAID-induced gastric ulcers in rheumatic patients, DRUGS TODAY, 36, 2000, pp. 73-78
Citations number
4
Categorie Soggetti
Pharmacology
Journal title
DRUGS OF TODAY
ISSN journal
00257656 → ACNP
Volume
36
Year of publication
2000
Supplement
A
Pages
73 - 78
Database
ISI
SICI code
0025-7656(200002)36:<73:TCSODV>2.0.ZU;2-D
Abstract
Two comparative clinical studies were carried out in rheumatic patients tak ing nonsteroidal antiinflammatory drugs (NSAIDs) in order to assess the eff icacy of dosmalfate vs. misoprostol, the reference gastroprotective drug, i n the prevention of NSAID-induced gastric ulcers. Dosmalfate proved to have a similar efficacy compared to misoprostol in preventing gastric damage in the rheumatic patients studied and was very well tolerated. (C) 2000 Prous Science. All rights reserved.