Construction of bicyclo[2.2.2]octanone systems by microwave-assisted solidphase Michael addition followed by Al2O3-mediated intramolecular aldolisation. An eco-friendly approach

Authors
Ranu, BC Guchhait, SK Ghosh, K Patra, A
Citation
Bc. Ranu et al., Construction of bicyclo[2.2.2]octanone systems by microwave-assisted solidphase Michael addition followed by Al2O3-mediated intramolecular aldolisation. An eco-friendly approach, GREEN CHEM, 2(1), 2000, pp. 5-6
Citations number
25
Categorie Soggetti
Chemistry
Journal title
GREEN CHEMISTRY
ISSN journal
14639262 → ACNP
Volume
2
Issue
1
Year of publication
2000
Pages
5 - 6
Database
ISI
SICI code
1463-9262(200002)2:1<5:COBSBM>2.0.ZU;2-#
Abstract
Microwave irradiation of a mixture of cyclohexenones and ethyl acetoacetate adsorbed on the surface of solid lithium S-(2)-prolinate which is then pla ced on a column of basic alumina leads to the stereoselective construction of bicyclo[2.2.2]octanone systems through Michael addition and subsequent i ntramolecular aldolisation.