Synthesis and microbiological activity of some 2H-1,4-benzothiazin-3-one derivatives

Authors
Guarda, VLD Perrissin, M Thomasson, F Ximenes, EA Galdino, SL Pitta, IR Luu-Duc, C
Citation
Vld. Guarda et al., Synthesis and microbiological activity of some 2H-1,4-benzothiazin-3-one derivatives, HETEROCYC C, 6(1), 2000, pp. 49-54
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLIC COMMUNICATIONS
ISSN journal
07930283 → ACNP
Volume
6
Issue
1
Year of publication
2000
Pages
49 - 54
Database
ISI
SICI code
0793-0283(2000)6:1<49:SAMAOS>2.0.ZU;2-R
Abstract
Synthesis, physical and analytical properties of 6-alkylacylamino-4-methyl- 2H-1,4-benzothiazin-3-one derivatives are described. These new compounds we re prepared by acylation and/or alkylation of the amino group by phase tran sfer catalysis. Acid hydrolysis of alkylacylamino-2H-1,4-benzothiazin-3-one s afforded N-alkylamino-benzothiazin-3-ones. Some of them were evaluated in vine for bacteriostatic activity.