The emerging role of IL-15 in NK-cell development

Authors
Liu, CC Perussia, B Young, JDE
Citation
Cc. Liu et al., The emerging role of IL-15 in NK-cell development, IMMUNOL TOD, 21(3), 2000, pp. 113-116
Citations number
25
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
21
Issue
3
Year of publication
2000
Pages
113 - 116
Database
ISI
SICI code
0167-5699(200003)21:3<113:TEROII>2.0.ZU;2-4
Abstract
Natural killer (NK) and T cells appear to have a common progenitor cell. In terleukin 15 (IL-15) plays an important role in directing such progenitors to commit to NK-cell differentiation. Several other cytokines such as Flt-3 ligand and IL-7 appear to modulate or enhance the effects of IL-15.