Background: The aim was to evaluate the characteristics of Wilms' tumor and
the results of combined modality treatment obtained in our center in Turke
y.
Methods: From January 1978 to December 1996, 106 patients with Wilms' tumor
were diagnosed. Of these 106 patients, 61 were male and 45 were female (M/
F = 1,35); the median age at diagnosis was 39 months, The distribution of t
he 106 patients according to clinical stage was stage 1 10%, stage II 42%,
stage III 35%, stage IV 9% and stage V 4%. Histologically, 102 of the cases
could be evaluated: favorable histology was diagnosed in 88.2% and unfavor
able histology in 11.8% of the patients. Ninety-eight patients were treated
according to NWTS and eight patients according to SIOP protocols.
Results: The EFS and overall survival rates at 2 years were 74.2 and 79.5%
respectively, and at 5 years 72.4 and 76.6% respectively.
Conclusion: As a developing country we evaluated our survival rates and rep
ort an improvement in treatment in recent years.