Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent

Authors
Kono, T Ishii, M Negoro, N Taniguchi, S
Citation
T. Kono et al., Scleroderma-like reaction induced by uracil-tegafur (UFT), a second-generation anticancer agent, J AM ACAD D, 42(3), 2000, pp. 519-520
Citations number
5
Categorie Soggetti
Dermatology,"da verificare
Journal title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN journal
01909622 → ACNP
Volume
42
Issue
3
Year of publication
2000
Pages
519 - 520
Database
ISI
SICI code
0190-9622(200003)42:3<519:SRIBU(>2.0.ZU;2-2
Abstract
UFT, a combination of uracil and tegafur, is a second-generation anticancer agent. UFT has been used in Japan, other Asian countries, South America, a nd Russia. Recently, UFT has been extensively studied for colorectal pancre atic, and various types of cancer in North America and Europe, especially w ith leukovorin. We report a case of a scleroderma-like reaction induced by long-term administration of UFT. This is the first report of UFT-induced sc leroderma-like reaction.